Trelles et al. While comparative studies are still lacking, combined treatment regimens seem to augment, and potentiate, the effect of each individual modality. Despite extensive literature regarding the safety and efficacy of minimally invasive photorejuvenation modalities, few published reports are available regarding their combined use. This study aimed to explore the safety and synergistic potential of sequential IPL and NAFL treatments with particular focus on skin texture, skin tone, and mean downtime.
All patients signed an approved version of an informed consent form. Healthy male or female patients with Fitzpatrick 10 skin type I—IV, within the age range of 30—65 years, with baseline elastosis scores of 3—6 and mild to moderate facial pigmentation, were considered eligible to participate in this study. Heavy smokers, pregnant, and breastfeeding women, women within 3 months of delivery or 6 weeks of discontinuing breastfeeding, individuals unlikely to refrain from tanning, and those receiving photoactive medication or who had recently received oral isotretinoin were not considered eligible to participate in the study.
Before all treatment sessions, prophylactic treatment was administered to patients with a history of herpes simplex. Facial skin was cleansed and frontal, right, and left side digital photographs were taken in controlled lighting conditions using standard photography equipment Canfield Omnia using a canon EOS Rebel T5i or FotoFinder with digital SLR camera and PolFlash. Immediately following treatment, cold air or cold, but not frozen, wet gauze pads were applied when necessary to cool the treated area.
A bland emollient was applied shortly after treatment without any dressing. Additionally, the patients were instructed to avoid sun exposure and refrain from using tanning booths, sprays, or creams throughout the study period.
Non-Ablative Fractional Treatments
Sunscreens with at least SPF 30 were to be used on a daily basis. Intervals of 4—6 weeks were enforced between treatment sessions. Patients rated pain and discomfort immediately after treatments using the visual analogue scale VAS 0, no pain; 10, intolerable pain. Patient social downtime was recorded at the following treatment session.
Changes from baseline were modeled as a function of baseline value and visit number using a repeated measure analysis of variance model. Downtime, comfort, satisfaction, and improvement ratings were modeled as a function of visit number using repeated measure analysis of variance models. Means and standard errors SE are presented. All three of these patients were excluded from the analysis. Pigmentation grading reflected a good to excellent response in most patients Improvements in mottled pigmentation were observed in The majority of patients reported none to moderate erythema and edema.
Mean social downtime was 1.
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No severe nor serious events were reported throughout the study period. Adverse events Table 2 considered definitely related to treatment included a single event of severe pruritus that began the day of treatment and resolved spontaneously without sequela within 7 days. Additionally, three cases of pinpoint bleeding mainly appeared over telangiectasia of the nose immediately after treatment and lasted from several seconds to 3 days before resolving with no residual effects. Finally, a single case of herpes simplex outbreak was reported one week following treatment, which resolved within 5 days.
A better understanding of the multifactorial nature of skin aging and its underlying cellular mechanisms has led dermatologists to begin implementing multiple treatment methods to address the cutaneous signs of photoaging. This prospective study was initiated to assess the hypothesized synergistic impact of combined IPL and NAFL treatment on photoaged skin. IPL is commonly deployed to address vascular and pigment changes, and to a lesser extent, to achieve skin smoothing. This technology is particularly associated with short downtimes and a high safety profile 13 - Tanaka et al.
Bitter et al.
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Negishi et al. NAFL treatment creates microscopic thermally damaged zones, while the surrounding unaffected tissue serves as an immediate source of viable cells for rapid repair and recovery 18 , This improvement was sustained over the ensuing 8 weeks, while no change from baseline in skin redness and pigmentation was noted As expected, our combination approach was found to be safe, tolerable, and associated with minimal downtime and side effects Table 2.
Wanner et al. An identical incidence of acneiform eruptions, all mild, was reported by Bencini et al.
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Only one of the 87 treated patients experienced hyperpigmentation, which cleared within 1 month. Clark et al. The mean fluence and density range applied in our study The limitations of this study relate to the lack of available studies for comparison. Performing both treatments back to back on the same day simplifies care for both patients and providers, reduces expenses, increases patient satisfaction, and shortens overall downtime. Volume 51 , Issue 2. The full text of this article hosted at iucr.
If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. If the address matches an existing account you will receive an email with instructions to retrieve your username. Lasers in Surgery and Medicine Volume 51, Issue 2. Clinical Reports Open Access. Conflict of Interest Disclosures: Dr. Knight and Dr.
Ablative Laser Resurfacing
Kautz speak on behalf of, and perform research for Lumenis Ltd. Tools Request permission Export citation Add to favorites Track citation. Before the procedure, your face will be thoroughly cleaned. The areas to be treated will be numbed with a local anesthetic to help reduce pain. You may also be given a sedative to help you relax.
You will wear protective eye shields during the procedure to protect your eyes. Your doctor will hold your skin taut while the laser is fired. The intense heat from the laser causes just the right amount of controlled damage to the small targeted area of skin. This removes aged or sun-damaged skin and at the same time, encourages healthy collagen to grow in its place. Ablative laser resurfacing typically takes between 30 minutes and two hours, depending on the technique used and the size of the area treated.
maisonducalvet.com/sitios-para-conocer-gente-de-el-astillero.php After laser resurfacing, an ointment and dressing will be applied to your skin. Your face will be covered with a mask bandage for a few days. Your skin will look and feel as though it is severely sunburned. It may be raw, oozing and have significant drainage for up to two weeks following laser resurfacing. You will be instructed on how to care for your skin during the initial healing process.
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It is important not to pick or scratch at the skin while it is healing. You may experience pain, tingling, burning and itching. You may use pain medicine and ice packs to relieve your pain. Remain at home and avoid strenuous activity. It is important to complete the antiviral medication that the doctor has given you to reduce the chance of infection. You will need to have multiple follow-up appointments so your doctor can monitor your recovery.
Non-Ablative Laser Skin Rejuvenation
It typically takes two to four weeks for your skin to completely heal. After about two weeks, new skin grows and covers the wounds. The skin can remain pink and red for many months after the procedures; however most patients can use makeup to cover the skin color after about two weeks.